… This has led to the assessment of a wide variety of approaches to malaria vaccine design …
-sporozoite vaccine is currently in phase III trials. However, a more effective malaria vaccine …

… malaria vaccine development in the past 5 years: reasons for cautious optimism, the type of
vaccine … , a deployable, effective malaria vaccine is a realistic medium-term to long-term goal. …

… A malaria vaccine would represent a public health tool that is viewed by some experts to be
… history of malaria vaccine development, then explain the malaria life cycle as a backdrop to …

… This study provided the first demonstration of a CTL epitope on a malaria parasite (53). … ,
and efficacy of a malaria sporozoite vaccine administered with monophosphoryl lipid A, cell wall …

… an effective malaria vaccine poses a major scientific challenge both in the laboratory and
in the field. Such a vaccine is necessary because of the massive disease burden of malaria in …

… Can we generate a vaccine that will take away the toxicity/severe pathology that occurs
amongst a fraction of malaria infected persons? Although the mechanism(s) that cause the …

… Malaria vaccine development has therefore focused on the development of a subunit
vaccine… the different strategies for developing a vaccine to the blood stage of malaria. Why is it …

… malaria antigens in subjects exposed previously to malaria infection. A potentially effective
way of using malaria vaccines with high initial efficacy but which provide only a short period …

… In 2015, the European Medicines Agency announced the adoption of a positive opinion for
the malaria vaccine candidate most advanced in development, RTS,S/AS01, which provides …

… not as a direct path to a malaria vaccine but as proof that a vaccine was possible, and as
justification for the ensuing decades of research aimed at identifying the “right” vaccine antigen …