ADP-ribosylation factor family of small GTP-binding proteins: Their membrane recruitment, activation, crosstalk and functions
Members of the ADP-ribosylation factor (ARF) family of guanine-nucleotide binding proteins
play critical roles in various cellular processes, especially in regulating the secretory, and
endocytic pathways. The fidelity of intracellular vesicular trafficking depends on proper
activations and precise subcellular distributions of ARF family proteins regulated by guanine
nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). Here we
review recent progress in understanding the membrane recruitment, activation, crosstalk …
play critical roles in various cellular processes, especially in regulating the secretory, and
endocytic pathways. The fidelity of intracellular vesicular trafficking depends on proper
activations and precise subcellular distributions of ARF family proteins regulated by guanine
nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). Here we
review recent progress in understanding the membrane recruitment, activation, crosstalk …
Members of the ADP-ribosylation factor (ARF) family of guanine-nucleotide binding proteins play critical roles in various cellular processes, especially in regulating the secretory, and endocytic pathways. The fidelity of intracellular vesicular trafficking depends on proper activations and precise subcellular distributions of ARF family proteins regulated by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). Here we review recent progress in understanding the membrane recruitment, activation, crosstalk, and functions of ARF family proteins.
Frontiers以上显示的是最相近的搜索结果。 查看全部搜索结果