The National AI Institute for Adult Learning and Online Education (AI‐ALOE) develops AI learning and teaching assistants to enhance the proficiency of adult reskilling and upskilling, and thereby transform workforce development. The AI assistants both address known problems in online education for reskilling/upskilling and help personalize adult learning for workforce development. AI‐ALOE develops new AI models and techniques for self‐explanation, machine teaching, and mutual theory of mind to make the AI assistants usable, learnable, teachable, and scalable. AI‐ALOE is also developing a data architecture for deploying and evaluating the AI assistants, collecting and analyzing data, and personalizing learning at scale.