We investigated the concentration and timing characteristics of chromium (Cr 3+) absorption in the presence of selenium (Se 4+) inside the cells as well as in lipids of Chlorella vulgaris microalgae. Discovered patterns of chromium accumulation had a pronounced fluctuation, which can be divided into four phases: cells' adaptation to the new factor, associated with membrane mechanisms of cell stress response formation; active accumulation phase, which ends after the saturation of binding sites with metal ions, first with metallothionein proteins; suppression controlled metal fixation particularly in the cell and in lipids; stage of accumulation recovery that is chaotic and uncontrolled by the cell and accompanied by its death.