Common variable immunodeficiency (CVID) is a heterogeneous disorder with decreased
production of immunoglobulins that presents with recurrent and serious infections in 90% of
cases. Review of the literature showed only 12 cases of gastrointestinal infection of
cytomegalovirus in patients with CVID. We present an unusual case of a CVID patient
presenting with new-onset hematochezia. With proper clinical suspicion and endoscopic
evaluation, cytomegalovirus colitis was diagnosed and acute bleeding was successfully …