The ethylacetate and n-butanol fractions of ethanolic extract of Platanus orientalis leaves led
to the isolation of new acylated flavonol glycoside as 3′, 5, 7-trihydroxy-4′-
methoxyflavonol 3-[O-2-O-(2, 4-Dihydroxy)-E-cinnamoyl-α-l-rhamnopyranosyl-(1→ 6)-β-d-
glucopyranosyl (1→ 2)]-β-d-glucopyranoside, along with seven known compounds. All the
compounds were characterized by NMR including 2D NMR techniques. The isolates were
evaluated for NF-κB, nitric oxide (NO), aromatase and QR2 chemoprevention activities and …

Background: Esophageal cancer (EC) is the sixth leading cause of death from cancer. In
high-risk regions, squamous cell carcinoma is the most common type of EC, and its etiology
remains poorly understood. It shows uneven geographical distribution in its occurrence,
reflecting the influence of local environmental conditions, lifestyle and genetic predisposition
in the development of the cancer. Kashmir, in the north of India, has been described as a
high-risk area for esophageal squamous cell carcinoma (ESCC). In the present investigation …