Adaptive optics compensation effect on the performance of an optical wireless communication system (OWC) employing M-ary pulse position modulation (PPM) scheme in anisotropic non-Kolmogorov turbulent atmosphere is investigated. Avalanche photodetector (APD) is used at the receiver side and log-normal channel that models the weak turbulence conditions is utilized. Anisotropy, generally resulting in better performance in OWC systems operating in the turbulent medium, combined with the adaptive optics applications will enhance the bit-error-rate (BER) of the OWC systems significantly. Results are obtained depending on various parameters for both the turbulent atmosphere and the receiver. Our work gives OWC system designers a perspective to optimize their design.