Adiponectin is associated with improvement of endothelial function after rosiglitazone treatment in non-diabetic individuals with metabolic syndrome
OBJECTIVE: The risks of metabolic syndrome (MetSyn) rely on the interaction between
insulin resistance, metabolic abnormalities, inflammation and vascular dysfunction. Insulin
sensitizers counteract some of these abnormalities. The objective of this study was to
evaluate the effects of rosiglitazone (ROSI) on vascular reactivity, adipokines and
inflammatory markers in a group of non-diabetic subjects with MetSyn. METHODS AND
RESULTS: Thirty subjects with NCEP-ATPIII criteria for MetSyn and eight healthy subjects …
insulin resistance, metabolic abnormalities, inflammation and vascular dysfunction. Insulin
sensitizers counteract some of these abnormalities. The objective of this study was to
evaluate the effects of rosiglitazone (ROSI) on vascular reactivity, adipokines and
inflammatory markers in a group of non-diabetic subjects with MetSyn. METHODS AND
RESULTS: Thirty subjects with NCEP-ATPIII criteria for MetSyn and eight healthy subjects …
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