Adipose stem cell tissue–engineered construct used to treat large anterior mandibular defect: a case report and review of the clinical application of good …
GK Sándor, VJ Tuovinen, J Wolff, M Patrikoski… - Journal of Oral and …, 2013 - Elsevier
PURPOSE: Large mandibular resection defects historically have been treated using
autogenous bone grafts and reconstruction plates. However, a major drawback of large
autogenous bone grafts is donor-site morbidity. PATIENTS AND METHODS: This report
describes the replacement of a 10-cm anterior mandibular ameloblastoma resection defect,
reproducing the original anatomy of the chin, using a tissue-engineered construct consisting
of β-tricalcium phosphate (β-TCP) granules, recombinant human bone morphogenetic …
autogenous bone grafts and reconstruction plates. However, a major drawback of large
autogenous bone grafts is donor-site morbidity. PATIENTS AND METHODS: This report
describes the replacement of a 10-cm anterior mandibular ameloblastoma resection defect,
reproducing the original anatomy of the chin, using a tissue-engineered construct consisting
of β-tricalcium phosphate (β-TCP) granules, recombinant human bone morphogenetic …
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