… We also demonstrate somatically mutated homotypic interactions, and possibly the CSP
structures that they stabilize, play a key role in the mechanism of protection from P. falciparum …

… finding that affinity-matured homotypic interactions in three … that L9 K -mediated homotypic
interactions are also critical for … value of 1, the cultures were induced with 1 mM isopropyl β-d-…

… understanding of repeat-induced homotypic interactions in the B … interactions combined
with extensive homotypic interactions … in the high-density 850 Fab-PfCSP cryoEM structure. …

… basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9. Nature
… Affinitymatured homotypic interactions induce spectrum of PfCSP structures that influence …

… -reactive binding and the induced PfCSP epitope conformation are … Homotypic interactions
between 3D11 Fabs stabilize the … Here, we analyze the structure and molecular interactions of …

… of repeat-induced homotypic interactions in the B cell … angle interactions combined with
extensive homotypic interactions … observed in the high-density 850 Fab-PfCSP cryoEM structure. …

… structure-function characterization of 12 VH3-33 anti-PfCSP monoclonal antibodies (mAbs)
with varying degrees of cross-reactivity induced … epitope conformations induced by antibody …

… -expressing feeder cells and cytokines to induce antibody secretion. Supernatants were …
our structure is the presence of affinity-matured antibody-antibody homotypic interactions in …

… the ProC6C vaccine-induced serum antibody binding … vaccine antigen, but PfCSP antibody
responses were not initially … to structures facilitating high affinity interactions between anti…

… serological profiles of protective responses in humans induced by RTS,S vaccination and …
next-generation CSP-based vaccines designed to induce both high quantity and high-quality …