Airway epithelial cell immunity is delayed during rhinovirus infection in asthma and COPD

PC Veerati, NM Troy, AT Reid, NF Li… - … in immunology, 2020 - frontiersin.org
… a delayed IFN response in asthmatic and COPD cells following low MOI RV-A1 infection.
Most … innate immune responses at early timepoints in cultures from healthy donors. In contrast …

Viral infection and airway epithelial immunity in asthma

SR Kim - International journal of molecular sciences, 2022 - mdpi.com
… the diverse roles of airway epithelial immunity and related potential … epithelial cells from
asthmatic patients were delayed rather … line with rhinovirus. Induction of cytokine release and …

Role of viral infections in asthma and chronic obstructive pulmonary disease

D Proud, CW Chow - American journal of respiratory cell and …, 2006 - atsjournals.org
… of rhinovirus infections between subjects with asthma and those without … (31), and acute
allergen challenge delayed onset and … Infection of a human respiratory epithelial cell line with …

Mechanism of rhinovirus immunity and asthma

Z Yang, H Mitländer, T Vuorinen, S Finotto - Frontiers in immunology, 2021 - frontiersin.org
Rhinovirus infects airway epithelial cells representing the … of chronic respiratory disease,
such as asthma and COPD. In … as the host immune system, during rhinovirus infection, induced …

Respiratory viral and bacterial exacerbations of COPD—the role of the airway epithelium

ME Love, D Proud - Cells, 2022 - mdpi.com
rhinovirus infection of epithelial cells obtained from bronchialairway epithelial IFN response
but to one which is delayed, … The delayed immune responses raise some questions about …

Rhinovirus‐induced exacerbations of asthma and COPD

MB Hershenson - Scientifica, 2013 - Wiley Online Library
… that rhinovirus infection induces airway epithelial cells to … infection of mucociliary-differentiated
airway epithelial cells … similar to COPD show delayed clearance of rhinovirus in vivo, …

The interplay between host immunity and respiratory viral infection in asthma exacerbation

FMA Hossain, JY Choi, E Uyangaa… - Immune …, 2019 - synapse.koreamed.org
infection including chronic obstructive pulmonary disease (… RV infection of isolated human
bronchial epithelial cells and … Rhinovirus infection induces interleukin-13 production from …

[PDF][PDF] 2. Airway epithelial cell immunity is delayed during rhinovirus infection in asthma and COPD

NM Troy - … the role of the immune system in asthma …, 2021 - research-repository.uwa.edu.au
… induction was maximal at or beyond 72-96 hours post infection. Thus, we … asthma and COPD
relate to delayed (rather than deficient) expression of epithelial cell innate antiviral immune

Airway epithelial orchestration of innate immune function in response to virus infection. A focus on asthma

AI Ritchie, DJ Jackson, MR Edwards… - Annals of the American …, 2016 - atsjournals.org
… , of which the most likely type is rhinovirus infection. This article focuses on the role played …
antiviral immune responses in the asthmatic respiratory epithelium are impaired (delayed and …

Deciphering respiratory-virus-associated interferon signaling in COPD airway epithelium

H Guo-Parke, D Linden, S Weldon, JC Kidney… - Medicina, 2022 - mdpi.com
immunity has been implicated in COPD airway epithelialAirway epithelium in asthma and
COPD patients have been … or delayed IFN-β and IFN-λ response to rhinovirus infection, as …