… swiftly in the airway epithelial compartment. Bronchial and alveolar epithelial cells mostly … , these data suggest that the airway epithelial cellsregulate the adjuvantactivity of flagellin. …
D Fougeron, L Van Maele, P Songhet, D Cayet, D Hot… - Vaccine, 2015 - Elsevier
… However, TLR5-mediated signaling specifically enhanced the maturation of lung dendritic … Our data suggest that PMNs do not regulate the flagellin's adjuvantactivity (as for the adjuvant …
X Li, Y Cao, M Mou, J Li, S Huang… - Journal of Leukocyte …, 2023 - academic.oup.com
… (FBS), the cells were stimulated with SF or the control protein SF△90 … demonstrated that the mucosaladjuvantactivity of SF in … to TLR5-mediated modulation of airway dendritic cells and …
… However, the mode of action of flagellin in the airwaymucosa (… demonstrated that the mucosal adjuvantactivity of flagellin … of mucosal CD103(+) DCs induces Foxp3(+) regulatory T cells …
Y Cao, E Zhang, J Yang, Y Yang, J Yu… - Journal of leukocyte …, 2017 - academic.oup.com
… When delivered via an in route, airwaystructuralcells—probably respiratory epithelial cells… the regulation of TLR5-mediatedmucosaladjuvantactivity by respiratory epithelial cells is …
… activity suggests that it may serve as an effective adjuvant for … a more effective mucosal response to respiratory infections (… an adjuvant during intranasal vaccination, flagellin regulated …
A Vijayan, L Van Maele, D Fougeron… - The Journal of …, 2020 - journals.aai.org
… In this study, we looked at how the airway epithelial cells (AECs) regulate the flagellin-… the structural AECs but does not have an impact on the alveolar macrophages. TLR5-mediated …
… a more effective mucosal response to respiratory infections (10,… flagellin as a potent mucosal adjuvant in our early life … be functionally enhanced by TLR5-mediatedregulation. Future …
P Losol, MH Ji, JH Kim, JP Choi, JE Yun, JH Seo… - World Allergy …, 2023 - Elsevier
… In vivo, intranasal administration of flagellin induced mucosal … due to its regulation of airway fibrosis and airway remodeling … epithelial cells contributed to TLR5-mediated dendritic cell …