Background: Several studies have shown that albuminuria is associated with increased risk
for fatal and nonfatal cardiovascular events, independent of conventional risk factors. The
partition values for urine albumin–creatinine ratio (UACR) used to identify microalbuminuria
have been based on studies that predicted risk in diabetic patients. Objective: To determine
whether the relation between albuminuria and cardiovascular risk can be used to predict
cardiovascular morbidity and mortality in hypertensive patients. Design: Multicenter cohort …

Albuminuria and cardiovascular risk in hypertensive patients with left ventricular
hypertrophy: The LIFE Study. Studies have shown that albuminuria is associated with
increased risk for cardiovascular events. We tested the relationship between albuminuria
(UACR) and cardiovascular risk in 8206 hypertensive patients with left ventricular
hypertrophy included in the LIFE Study. Follow-up was 39,122 patient years. The risk for the
primary composite cardiovascular end point increases continuously from the lowest to the …