Alkylhydroperoxide reductase of Helicobacter pylori as a biomarker for gastric patients with different pathological manifestations

CH Huang, MH Chuang, WL Lo, MS Wu, YH Wu… - Biochimie, 2011 - Elsevier
The development of various gastrointestinal diseases was suggested to be associated with
chronic inflammation as a consequence of Helicobacter pylori (H. pylori) infection. Our
previous studies showed that an antioxidant protein alkylhydroperoxide reductase (AhpC) is
an abundant and important antioxidant protein present in H. pylori. In this study we have
explored the potential of utilizing antibodies to AhpC for detection of patients who are at high
risks of evolving into severe outcomes of gastric malignancies after H. pylori infection. The …
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