Alpha lipoic acid attenuates radiation-induced thyroid injury in rats

JH Jung, J Jung, SK Kim, SH Woo, KM Kang… - PLoS …, 2014 - journals.plos.org
… Exposure of the thyroid to radiation during radiotherapy of the head and neck is often … of
α-lipoic acid (ALA) on radiation-induced thyroid injury in rats. Rats were randomly assigned to …

Alpha-lipoic acid effectively attenuates ionizing radiation-mediated testicular dysfunction in rats: Crosstalk of NF-ĸB, TGF-β, and PPAR-ϒ pathways

RS Said, HA Mohamed, DH Kassem - Toxicology, 2020 - Elsevier
… Thus, we investigated the therapeutic potential of LA against radiation-induced testicular
toxicity and studied how LA supplementation would influence spermatogenesis, testicular …

The radioprotective effects of alpha-lipoic acid on radiotherapy-induced toxicities: a systematic review

S Sheikholeslami, S Khodaverdian, M Dorri-Giv… - International …, 2021 - Elsevier
… mortality in rats to a much greater extent than the alone irradiated … effects of alpha-lipoic
acid on radiation-induced toxicities. The … Alpha-lipoic acid attenuates the increased levels of …

Alpha-lipoic acid ameliorates radiation-induced salivary gland injury by preserving parasympathetic innervation in rats

JH Kim, BK Jeong, SJ Jang, JW Yun, MH Jung… - International journal of …, 2020 - mdpi.com
… to reduce radiation-induced toxicity in normal tissues. In this study, we investigated the effect
of ALA on radiation-induced SG dysfunction. Male Sprague–Dawley rats were assigned to …

Alpha-lipoic acid ameliorates radiation-induced lacrimal gland injury through NFAT5-dependent signaling

H Kim, WS Yoo, JH Jung, BK Jeong, SH Woo… - International journal of …, 2019 - mdpi.com
… ALA attenuated the increase in phosphorylated p38 and pJNK expression and the decrease
… Finally, the radiation-induced dry eye rat model is not a standardized dry eye model. Fine …

Neuroprotective effects of alpha-lipoic acid on radiation-induced brainstem injury in rats

E Motallebzadeh, F Aghighi, Z Vakili… - Research in …, 2023 - journals.lww.com
Alpha-lipoic acid can neutralize free radicals directly and has been shown to reduce
radiation-induced oxidative stress[ 21 ]. Given that ionizing radiation induces oxidative stress via the …

Protective effect of alpha-lipoic acid on salivary dysfunction in a mouse model of radioiodine therapy-induced sialoadenitis

JH Jung, JH Kim, MH Jung, SW Kim, BK Jeong… - International Journal of …, 2020 - mdpi.com
alpha lipoic acid (ALA) administered prior to RI therapy in a mouse model of RI-induced
sialadenitis. Four-week-old female C57BL/6 mice … ALA on radiation-induced the thyroid tissue in …

[HTML][HTML] Alpha lipoic acid attenuates radiation-induced oral mucositis in rats

JH Kim, MH Jung, JP Kim, HJ Kim, JH Jung, JR Hahm… - Oncotarget, 2017 - ncbi.nlm.nih.gov
alpha lipoic acid (ALA) could protect against radiation-induced oral mucositis in a rat model.
… been reported that alpha lipoic acid (ALA) protects against radiation-induced normal tissue …

[HTML][HTML] Evaluating the protective effect of resveratrol, Q10, and alpha-lipoic acid on radiation-induced mice spermatogenesis injury: A histopathological study

M Najafi, M Cheki, P Amini, A Javadi… - International Journal …, 2019 - ncbi.nlm.nih.gov
… , alpha-lipoic acid, and Q10 have the potential to reduce some of the side effects of radiation
on mice spermatogenesis. … in mice small intestine, attenuate mucositis, and salivary glands …

Mitigation of radiation-induced pneumonitis and lung fibrosis using alpha-lipoic acid and resveratrol

R Azmoonfar, P Amini, R Yahyapour… - Anti-Inflammatory & …, 2020 - ingentaconnect.com
… of alpha-lipoic acid, resveratrol and their combination on mice … of radiation-induced salivary
glands, thyroid and intestinal … Alpha-lipoic acid and its combinational form could attenuate