Chronic pain can be associated with movement abnormalities. The primary motor cortex
(M1) has an essential role in the formulation and execution of movement. A number of
changes in M1 function have been reported in studies of people with chronic pain. This
review systematically evaluated the evidence for altered M1 structure, organization, and
function in people with chronic pain of neuropathic and non-neuropathic origin. Database
searches were conducted and a modified STrengthening the Reporting of OBservational …