[HTML][HTML] Ambulatory monitoring of heart sounds via an implanted device is superior to auscultation for prediction of heart failure events

M Cao, RS Gardner, R Hariharan, DG Nair… - Journal of cardiac …, 2020 - Elsevier
Background We compared the relationship between the third heart sound (S3) measured by
an implantable cardiac device (devS3) and auscultation (ausS3) and evaluated their
prognostic powers for predicting heart failure events (HFEs). Methods and Results In the
MultiSENSE study, devS3 was measured daily with continuous values, whereas ausS3 was
assessed at study visits with discrete grades. They were compared among patients with and
without HFEs at baseline and against each other directly. Cox proportional hazard models …
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