• Therapeutic administration of amiodarone, an antiarrhythmic drug, to eight patients
resulted in the formation of vortex-like figures within the anterior cornea. Clinical
examination disclosed no visual loss or other ocular abnormality attributable to the drug. In
one patient, light and transmission electron microscopy of corneal epithelium, bulbar
conjunctiva, and cataractous lens revealed complex lipid deposits within lysosome-like
intracytoplasmic inclusions in corneal, conjunctival, and lens epithelium, conjunctival …