An approach to the conditional error rate principle with nuisance parameters

G Gutjahr, W Brannath, P Bauer - Biometrics, 2011 - academic.oup.com
Biometrics, 2011academic.oup.com
In the presence of nuisance parameters, the conditional error rate principle is difficult to
apply because of the dependency of the conditional error function of the preplanned test on
nuisance parameters. To use the conditional error rate principle with nuisance parameters,
we propose to search among tests that guarantee overall error control for the test that
maximizes a weighted combination of the conditional error rates over possible values of the
nuisance parameters. We show that the optimization problem that defines such a test can be …
Summary
In the presence of nuisance parameters, the conditional error rate principle is difficult to apply because of the dependency of the conditional error function of the preplanned test on nuisance parameters. To use the conditional error rate principle with nuisance parameters, we propose to search among tests that guarantee overall error control for the test that maximizes a weighted combination of the conditional error rates over possible values of the nuisance parameters. We show that the optimization problem that defines such a test can be solved efficiently by existing algorithms.
Oxford University Press
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