Autophagy is a conserved degradation pathway that is involved in the maintenance of
normal cell differentiation and development. The Saccharomyces cerevisiae ATG5 gene is
an important component of the autophagy process. In this study, we identified MgATG5 as
an autophagy-related gene in Magnaporthe oryzae that is homologous to ATG5. Using
targeted gene replacement, an Mgatg5∆ mutant was generated and fungal autophagy was
blocked. Cytological analysis revealed that the mutant had poor fungal morphogenic …

Autophagy is a conserved degradation pathway that is involved in the maintenance of
normal cell differentiation and development. The Saccharomyces cerevisiae ATG5 gene is
an important component of the autophagy process. In this study, we identified MgATG5 as
an autophagy-related gene in Magnaporthe oryzae that is homologous to ATG5. Using
targeted gene replacement, an Mgatg5 Δ mutant was generated and fungal autophagy was
blocked. Cytological analysis revealed that the mutant had poor fungal morphogenic …