Colorectal cancer (CRC) is a leading cause of morbidity and mortality worldwide. The
majority of CRC deaths are caused by tumor metastasis, even following treatment. There is
strong evidence for epigenetic changes, such as DNA methylation, accompanying CRC
metastasis and poorer patient survival. Earlier detection and a better understanding of
molecular drivers for CRC metastasis are of critical clinical importance. Here, we identify a
signature of advanced CRC metastasis by performing whole genome-scale DNA …