An evaluation of the effectiveness of perampanel in people with epilepsy who have previously undergone resective surgery and/or implantation of a vagal nerve …

GD Jones, I Stavropoulos, K Ibrahim, M Tristram… - Epilepsy & Behavior, 2021 - Elsevier
About 30% of people with epilepsy (PWE) are drug-resistant. Those with focal seizures may
be suitable for epilepsy surgery. Those not amenable to resective surgery can be
considered for vagus nerve stimulation (VNS). However, after operative procedures, around
50% of patients continue to experience seizures. A multi-center retrospective study
assessing perampanel effectiveness and tolerability for PWE who have undergone surgical
resection and/or VNS implantation was performed. The primary outcome was≥ 50 …
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