This paper introduces and presents validation of the Constant Pressure Sequential Combustion system (denoted CPSC), a second generation concept developed for and applied to the new Ansaldo GT36 H-class gas turbine combustors. It has evolved from the well-established sequential burner technology applied to all current GT26 and GT24 gas turbines, and contains all architectural improvements implemented since original inception of this engine frame in 1994, with beneficial effects on the operation turndown, fuel flexibility, on the overall system robustness, and featuring the required aspects to stay competitive in the present day energy market. The applied air and fuel management therefore facilitate emission and dynamics control at both the extremely high and low firing temperature ranges required for existing and future Ansaldo gas turbine engine classes.