An open-label randomized controlled clinical trial for comparison of continuous phenylephrine versus norepinephrine infusion in prevention of spinal hypotension …
MC Vallejo, AF Attaallah, OM Elzamzamy… - International journal of …, 2017 - Elsevier
Background During spinal anesthesia for cesarean delivery phenylephrine is the
vasopressor of choice but can cause bradycardia. Norepinephrine has both β-and α-
adrenergic activity suitable for maintaining blood pressure with less bradycardia. We
hypothesized that norepinephrine would be superior to phenylephrine, requiring fewer
rescue bolus interventions to maintain blood pressure. Methods Eighty-five parturients
having spinal anesthesia for elective cesarean delivery were randomized to Group P …
vasopressor of choice but can cause bradycardia. Norepinephrine has both β-and α-
adrenergic activity suitable for maintaining blood pressure with less bradycardia. We
hypothesized that norepinephrine would be superior to phenylephrine, requiring fewer
rescue bolus interventions to maintain blood pressure. Methods Eighty-five parturients
having spinal anesthesia for elective cesarean delivery were randomized to Group P …
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