Analysis of pH and salt concentration on structural and model-drug delivery properties of polysaccharide-based multilayered films
This paper explores the influence of pH and ionic strength of polyelectrolyte solutions as a
simple and chemically amenable strategy for tuning the structure and drug delivery
properties of polyelectrolyte multilayers produced via layer-by-layer technique.
Carboxymethylcellulose/chitosan films were buildup under different pH (4.0 and 6.0) and
salt concentrations (0 or 0.2 M NaCl) conditions. Systematic data analyses using Design of
Experiments indicate that high ionic strength favors the formation of thinner and rougher …
simple and chemically amenable strategy for tuning the structure and drug delivery
properties of polyelectrolyte multilayers produced via layer-by-layer technique.
Carboxymethylcellulose/chitosan films were buildup under different pH (4.0 and 6.0) and
salt concentrations (0 or 0.2 M NaCl) conditions. Systematic data analyses using Design of
Experiments indicate that high ionic strength favors the formation of thinner and rougher …