In this research, we will present the results of the Covid-19 case data in January 2021 on the Prizren region. We have provided positive, negative, recovered, death cases database of Covid-19. This database is based on the Kosovo Institute of Health in Prizren. Initially, we will make descriptive statistical analyzes for all cases, illustrating them with graphs and tables. Then, we will analyze the normal distribution of cases with Covid-19 and finally the relationship between municipalities and cases through Chi-Square and ANOVA tests. To examine the differences between municipalities, the results of the Tukey test were used. As a result of the research, we found out 1117 positive cases, 1302 negative cases, 768 recovered cases, 33 death cases during January 2021, in the Prizren region. According to the normal distribution it turns out that there are numerous deviations from the regression line. Also, according to the tests Chi-Square and ANOVA, it turns out that there is a relationship between cases with Covid-19 and municipalities.