Analysis of the human adult urinary metabolome variations with age, body mass index, and gender by implementing a comprehensive workflow for univariate and …

EA Thévenot, A Roux, Y Xu, E Ezan… - Journal of proteome …, 2015 - ACS Publications
… evidenced by correlation analysis, and they allowed stratification of the cohort. In conclusion,
our study highlights the impact of gender and age on the urinary metabolome, and thus it …

Individual variability in human urinary metabolites identifies age‐related, body mass index‐related, and sex‐related biomarkers

T Wang, L Tang, R Lin, D He, Y Wu… - … Genetics & Genomic …, 2021 - Wiley Online Library
… To systematically investigate the variation of urine metabolites, a total of 183 human adults
… comprehensive analysis of urine metabolome physiological variations, and identified 30 age-…

Cross-classification of human urinary lipidome by sex, age, and body mass index

K Okemoto, K Maekawa, Y Tajima, M Tohkin, Y Saito - PLoS One, 2016 - journals.plos.org
human urine metabolome in healthy subjects. In this study, we performed cross-classification
of urinary … in the present study [16]; however, sex-related differences in the urinary oxylipins …

Analysis of the adult human plasma metabolome

KA Lawton, A Berger, M Mitchell, KE Milgram… - …, 2008 - Taylor & Francis
… , urine), such knowledge permits an efficient, metabolomics-… The current study underscores
the power of metabolomics to … of a population and changes in that profile with age, sex and …

Comparative blood and urine metabolomics analysis of healthy elderly and young male Singaporeans

L Chen, J Zhang, JPY Teh, BK Cheon… - Journal of proteome …, 2020 - ACS Publications
… , the urinary metabolome of elderly adults was characterized … the relative variation in blood
and urine metabolome of the … of amino acid and lipid metabolism in aging. In addition, the …

Determinants of the urinary and serum metabolome in children from six European populations

CHE Lau, AP Siskos, L Maitre, O Robinson… - BMC medicine, 2018 - Springer
… gap, metabolomic analyses of serum and urine were … weight measurements were converted
to body mass index (… Given the stark differences in the metabolic phenotypes between …

Urinary metabolic signatures of human adiposity

P Elliott, JM Posma, Q Chan, I Garcia-Perez… - Science translational …, 2015 - science.org
… Exploratory analysis of the urinary metabolome using 1 H … 5 to 2.0 × 10 −36 ) with body mass
index (BMI); 25 of these species … interindividual blood pressure variation and cardiovascular …

[HTML][HTML] The human urine metabolome

S Bouatra, F Aziat, R Mandal, AC Guo, MR Wilson… - PloS one, 2013 - journals.plos.org
… obtained for this study, the urine metabolome database (… show such variations based on
the populations (age, gender) … study on the contributions to the observed variations in urine is …

A metabolomics analysis of body mass index and postmenopausal breast cancer risk

SC Moore, MC Playdon, JN Sampson… - JNCI: Journal of the …, 2018 - academic.oup.com
… controls based on age at random assignment to the study arm (… , our results specifically
implicate changes in the metabolism … Trends in adult body-mass index in 200 countries from 1975 …

Investigation of the urinary metabolic variations and the application in bladder cancer biomarker discovery

X Liu, X Cheng, X Liu, L He, W Zhang… - … journal of cancer, 2018 - Wiley Online Library
study, we explored the urine metabolome in a cohort of 203 health adults, 6 patients with
benign bladder … the sex, age, body mass index (BMI),3, 4 and even the humans' chronotype or …