Animal models for SARS-CoV-2

CY Lee, AC Lowen - Current opinion in virology, 2021 - Elsevier
mouse ACE2 promoters [13 • ,18,28, 29, 30,31 • ]. The transgenic mouse models are susceptible
to SARS-CoV-2 … In particular, SARS-CoV-2 infection in some transgenic mouse models

Animal models in SARS-CoV-2 research

H Chu, JFW Chan, KY Yuen - Nature methods, 2022 - nature.com
… Similarly, transmission and vaccine studies can be evaluated only through
physiologically relevant animal models. In this Comment, we highlight key animal models …

A mouse model of SARS-CoV-2 infection and pathogenesis

SH Sun, Q Chen, HJ Gu, G Yang, YX Wang… - Cell host & …, 2020 - cell.com
… an animal model. Human angiotensin-converting enzyme II (ACE2) has been identified as
a functional receptor for SARS-CoV-2. In this study, we generated a mouse model expressing …

Animal models for SARSCoV2 research: a comprehensive literature review

K Pandey, A Acharya, M Mohan, CL Ng… - Transboundary and …, 2021 - Wiley Online Library
… of human SARS-CoV-2 infection are urgently needed. In this review, we outline animal models
that … Importantly, we discuss models that are appropriate for SARS-CoV-2 as well as the …

Animal models of mechanisms of SARSCoV2 infection and COVID‐19 pathology

SJ Cleary, SC Pitchford, RT Amison… - British journal of …, 2020 - Wiley Online Library
… development and reported approaches to model SARS-CoV-2 infection responses. We then
identify key areas in which studies using animal models might improve the reproduction of …

[HTML][HTML] Animal models of SARS-CoV-2 transmission

RD de Vries, B Rockx, BL Haagmans, S Herfst… - Current Opinion in …, 2021 - Elsevier
… , SARS-CoV-2 transmission and transmission intervention studies in animal models remain
scarce and have mostly been performed with the classical variant of SARS-CoV-2. Zhou et al…

[HTML][HTML] In vitro and animal models for SARS-CoV-2 research

K Takayama - Trends in pharmacological sciences, 2020 - cell.com
… An in vitro cell model for SARS-CoV-2 research is essential for understanding the viral
life … SARS-CoV-2, as well as organoids that can be used to examine the effects of SARS-CoV-2

The mechanisms and animal models of SARS-CoV-2 infection

W Jia, J Wang, B Sun, J Zhou, Y Shi… - Frontiers in Cell and …, 2021 - frontiersin.org
… characteristics of SARS-CoV-2. In addition, we focus on the mechanisms of SARS-CoV-2
infection… Finally, we introduce the research progress of animal models of COVID-19, aiming at a …

Cell and animal models of SARS-CoV-2 pathogenesis and immunity

SR Leist, A Schäfer… - Disease models & …, 2020 - journals.biologists.com
… The development of animal models will expedite our … -molecule SARS-CoV-2 inhibitors,
biologics such as SARS-CoV-2-… cell and animal models for studying SARS-CoV-2 infection and …

Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development

M Imai, K Iwatsuki-Horimoto, M Hatta… - Proceedings of the …, 2020 - National Acad Sciences
… of hamsters did not die upon SARS-CoV-2 infection, which is … COVID-19 hamster
models with comorbidities such as … hamster model will be useful for understanding SARS-CoV-2