… structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies

I Mercurio, V Tragni, F Busto, A De Grassi… - Cellular and Molecular …, 2021 - Springer
… The proposed complete IgG chimeric antibodies were obtained by superimposing the above…
-1/2 RBD, to the 3D atomic model of a crystallized IgG, available on the PDB (1igt.pdb, [56]) …

Comparative Analysis and Classification of SARS-CoV-2 Spike Protein Structures in PDB

M Aslam, MS Nawaz, P Fournier-Viger, W Li - COVID, 2023 - mdpi.com
… (antibodies, T-cell receptors and small molecules) used on the structures. We believe that
obtained … In Table 3, the structures 6NB3, 6NB4 and 6NB6, 6NB7 are the S protein structures …

[HTML][HTML] Evolution of antibody immunity to SARS-CoV-2

C Gaebler, Z Wang, JCC Lorenzi, F Muecksch, S Finkin… - Nature, 2021 - nature.com
… produced by memory B cells after 6.2 months, we obtained 532 paired antibody heavy and
… The frequency distributions of human V genes in anti-SARS-CoV-2 antibodies from this study …

Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain

KG Nabel, SA Clark, S Shankar, J Pan, LE Clark… - Science, 2021 - science.org
antibody S309 (44), a class 3 antibody that binds the RBD but does not interfere with ACE2
binding and from which the therapeutic antibody sotrovimab is derived, … (PDB ID 6NB6) (78) …

Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination

A Cho, F Muecksch, D Schaefer-Babajew, Z Wang… - Nature, 2021 - nature.com
… We also compared the affinity for pairs of antibodies obtained from persisting clones at 1.3 …
The frequency distributions of human V genes in anti-SARS-CoV-2 antibodies from this study …

[HTML][HTML] Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies

CO Barnes, AP West, KE Huey-Tubman… - Cell, 2020 - cell.com
… Overall, our studies structurally define a recurrent anti-SARS-CoV-2 antibody class derived
from VH3-53/VH3-66 and similarity to a SARS-CoV VH3-30 antibody, providing criteria for …

Convergent antibody responses to SARS-CoV-2 in convalescent individuals

DF Robbiani, C Gaebler, F Muecksch, JCC Lorenzi… - Nature, 2020 - nature.com
… We obtained 534 paired IgG heavy and light chain (IGH and … anti-SARS-CoV-2 antibodies,
we expressed 94 representative … The SARS-CoV monoclonal antibody S230 (PDB 6NB6) is …

mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants

Z Wang, F Schmidt, Y Weisblum, F Muecksch… - Nature, 2021 - nature.com
… to vaccination, we obtained 1,409 paired antibody heavy and … V genes in anti-SARS-CoV-2
antibodies from this study were … , and from PDB 6VYB and6NB6. Cryo-EM maps associated …

Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination

D Schaefer-Babajew, Z Wang, F Muecksch, A Cho… - Nature, 2023 - nature.com
… , we produced 178 representative monoclonal antibodies obtained from five individuals as
… The frequency distribution of human V genes in anti-SARS-CoV-2 antibodies from this study …

Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost

F Muecksch, Z Wang, A Cho, C Gaebler, T Ben Tanfous… - Nature, 2022 - nature.com
… potency and breadth when compared with antibodies obtained after the second dose. Notably,
… The frequency distributions of human V genes in anti-SARS-CoV-2 antibodies from this …