Anti-Bacterial and Anti-Fungal Activity of Xanthones Obtained via Semi-Synthetic Modification of α-Mangostin from Garcinia mangostana
S Narasimhan, S Maheshwaran, IA Abu-Yousef… - Molecules, 2017 - mdpi.com
The microbial contamination in food packaging has been a major concern that has paved
the way to search for novel, natural anti-microbial agents, such as modified α-mangostin. In
the present study, twelve synthetic analogs were obtained through semi-synthetic
modification of α-mangostin by Ritter reaction, reduction by palladium-carbon (Pd-C),
alkylation, and acetylation. The evaluation of the anti-microbial potential of the synthetic
analogs showed higher bactericidal activity than the parent molecule. The anti-microbial …
the way to search for novel, natural anti-microbial agents, such as modified α-mangostin. In
the present study, twelve synthetic analogs were obtained through semi-synthetic
modification of α-mangostin by Ritter reaction, reduction by palladium-carbon (Pd-C),
alkylation, and acetylation. The evaluation of the anti-microbial potential of the synthetic
analogs showed higher bactericidal activity than the parent molecule. The anti-microbial …
Anti-bacterial and anti-fungal activity of xanthones obtained via semi-synthetic modification of α-mangostin from Garcinia mangostana.
SN Srinivasan Narasimhan… - 2017 - cabidigitallibrary.org
The microbial contamination in food packaging has been a major concern that has paved
the way to search for novel, natural anti-microbial agents, such as modified α-mangostin. In
the present study, twelve synthetic analogs were obtained through semi-synthetic
modification of α-mangostin by Ritter reaction, reduction by palladium-carbon (Pd-C),
alkylation, and acetylation. The evaluation of the anti-microbial potential of the synthetic
analogs showed higher bactericidal activity than the parent molecule. The anti-microbial …
the way to search for novel, natural anti-microbial agents, such as modified α-mangostin. In
the present study, twelve synthetic analogs were obtained through semi-synthetic
modification of α-mangostin by Ritter reaction, reduction by palladium-carbon (Pd-C),
alkylation, and acetylation. The evaluation of the anti-microbial potential of the synthetic
analogs showed higher bactericidal activity than the parent molecule. The anti-microbial …