Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo

W Chun-Guang, Y Jun-Qing, L Bei-Zhong… - European journal of …, 2010 - Elsevier
Emodin (1, 3, 8-trihydroxy-6-methyl-anthraquinone), a natural anthraquinone derivative
isolated from Rheum palmatum L, has been reported to exhibit anti-cancer effect on several
human cancers such as liver cancers and lung cancers. However, the molecular
mechanisms of emodin-mediated tumor regression have not been fully defined. Our
preliminary study showed that emodin had highly cytotoxic effect on human chronic myeloid
leukemia K562 cell lines. This study was performed to investigate the anti-tumor effect of …

Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo.

WCG Wang ChunGuang, YJQ Yang JunQing… - 2010 - cabidigitallibrary.org
Abstract Emodin (1, 3, 8-trihydroxy-6-methyl-anthraquinone), a natural anthraquinone
derivative isolated from Rheum palmatum L, has been reported to exhibit anti-cancer effect
on several human cancers such as liver cancers and lung cancers. However, the molecular
mechanisms of emodin-mediated tumor regression have not been fully defined. Our
preliminary study showed that emodin had highly cytotoxic effect on human chronic myeloid
leukemia K562 cell lines. This study was performed to investigate the anti-tumor effect of …
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