Antibiotic production in Streptomyces is organized by a division of labor through terminal genomic differentiation

Z Zhang, C Du, F de Barsy, M Liem, A Liakopoulos… - Science …, 2020 - science.org
antibiotic production in colonies of Streptomyces coelicolor is coordinated by a division of
labor… Cells with chromosomal changes produce diversified secondary metabolites and secrete …

Ecological drivers of division of labour in Streptomyces

MF Traxler, DE Rozen - Current Opinion in Microbiology, 2022 - Elsevier
divisions of labour that structure antibiotic production. We … of spatially organised microbial
division of labour is seen in … : how do isogenic cells organise themselves into larger spatial …

Antibiotic production in Streptomyces is organized by a division of labour through terminal genomic differentiation

Z Zhang, C Du, F de Barsy, M Liem, A Liakopoulos… - bioRxiv, 2019 - biorxiv.org
… that antibiotic production in colonies of the multicellular bacterium Streptomyces coelicolor is
coordinated by a division of labour. We … Cells with gross chromosomal changes produce an …

Genetic network architecture and environmental cues drive spatial organization of phenotypic division of labor in Streptomyces coelicolor

VM Zacharia, Y Ra, C Sue, E Alcala, JN Reaso… - MBio, 2021 - Am Soc Microbiol
… in divisions of labor in colonies of Streptomyces coelicolor, a multicellular bacterium capable
of synthesizing an array of antibioticsUsing fluorescent reporters, we demonstrate that the …

The regulation of antibiotic production in Streptomyces coelicolor A3 (2)

M Bibb - Microbiology, 1996 - microbiologyresearch.org
… , was conducted in the author’s laboratory, and apologies are given to those whose work is
not … Since the N-terminal region of AfsR is homologous to ActII-ORF4 and RedD, this might …

Streptomyces inside-out: a new perspective on the bacteria that provide us with antibiotics

KF Chater - … Transactions of the Royal Society B …, 2006 - royalsocietypublishing.org
… In this section, three special features of Streptomyces biology … mycelium; the production of
antibiotics; and the production of … coelicolor A3(2) with an amino-terminal domain that lacks a …

Streptomyces

KF Chater, DA Hopwood - Bacillus subtilis and Other Gram …, 1993 - Wiley Online Library
… by streptomycetes have relatively long N-terminal signal … organization of the sets of genes
for biosynthesis of several diverse antibiotics has been one of the successes of Streptomyces

Molecular regulation of antibiotic biosynthesis in Streptomyces

G Liu, KF Chater, G Chandra, G Niu… - … and molecular biology …, 2013 - Am Soc Microbiol
… This paradigm has held over the last 2 decades, during which hundreds more … via its N-terminal
winged helix-turn-helix (HTH) domain and activates transcription through a C-terminal

The division of labor in microorganisms: from survival strategies of the species to industrial success stories

F Beltrametti - 2022 - boa.unimib.it
… every level of the biological organization, from the individuals of a … This is because these
groups are characterized by terminal … In the model actinomycete Streptomyces coelicolor, it was …

The Best of Both Worlds—Streptomyces coelicolor and Streptomyces venezuelae as Model Species for Studying Antibiotic Production and Bacterial Multicellular …

S Schlimpert, MA Elliot - Journal of Bacteriology, 2023 - Am Soc Microbiol
antibiotic production and development in Streptomyces and … cellular dynamics and cell
organization. These innovations in … , and the cytoplasmic organization of protein complexes. …