[HTML][HTML] Antibody isotype diversity against SARS-CoV-2 is associated with differential serum neutralization capacities

MG Noval, ME Kaczmarek, A Koide… - Scientific Reports, 2021 - nature.com
… , antibody isotypes (IgG, IgM, and IgA), and neutralization, we … associated to effective
SARS-CoV-2 neutralization. In this study, we obtained convalescent serum from 101 SARS-CoV-2

[HTML][HTML] Clinical and antibody characteristics reveal diverse signatures of severe and non-severe SARS-CoV-2 patients

H Wang, D Yan, Y Li, Y Gong, Y Mai, B Li, X Zhu… - Infectious Diseases of …, 2022 - Springer
… of anti-SARS-CoV-2 antibody isotypes and IgG subtypes. … whether the serum antibody could
block SARS-CoV-2 RBD to … were helpful for virus neutralization by blocking the interaction …

Differential antibody dynamics to SARS-CoV-2 infection and vaccination

Y Chen, P Tong, NB Whiteman, AS Moghaddam… - bioRxiv, 2021 - biorxiv.org
… produced in the context of different IgH isotypes (eg IgM, IgG, IgA). … decayer cross-variant
SARS-CoV-2 neutralization ability of the … breadth across a diversity of SARS-CoV-2 variants. …

[HTML][HTML] BNT162b2-induced neutralizing and non-neutralizing antibody functions against SARS-CoV-2 diminish with age

TA Bates, P Lu, YJ Kang, D Schoen, M Thornton… - Cell Reports, 2022 - cell.com
… Vaccination induces neutralization and Fc effector functions against SARS-CoV-2 … This
is associated with post-translational afucosylation and sialylation of vaccine-specific …

[HTML][HTML] Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection

A Zhang, HD Stacey, MR D'Agostino, Y Tugg… - Nature Reviews …, 2023 - nature.com
… IgG is the most abundant antibody isotype in human serum, … affinity and neutralization
potency may explain their differential … The diversity of epitopes that can be bound by antibodies

Sex disparities and neutralizing-antibody durability to SARS-CoV-2 infection in convalescent individuals

AJ Markmann, N Giallourou, DR Bhowmik, YJ Hou… - Msphere, 2021 - Am Soc Microbiol
isotype-specific IgA and, to a lesser extent, IgM antibodies … these studies with a more diverse
and representative population. … as a correlate of SARS-CoV-2 functional neutralization. The …

[HTML][HTML] Distinct early serological signatures track with SARS-CoV-2 survival

C Atyeo, S Fischinger, T Zohar, MD Slein, J Burke… - Immunity, 2020 - cell.com
… and subclasses, Fcγ-receptor binding profiles, neutralization, … simultaneously contribute to
differential control and clearance … individuals leverage isotype and subclass diversification in a …

Immunogenic profile of SARS-CoV-2 spike in individuals recovered from COVID-19

JA Juno, HX Tan, WS Lee, A Reynaldi, HG Kelly… - medRxiv, 2020 - medrxiv.org
… (C) Isotype distribution of spike + RBD − and spike + RBD + … share significant homology,
but with marked diversity within … coloured in proportion to plasma neutralization titres. (C) …

[HTML][HTML] Increased resistance of SARS-CoV-2 Omicron variant to neutralization by vaccine-elicited and therapeutic antibodies

T Tada, H Zhou, BM Dcosta, MI Samanovic… - …, 2022 - thelancet.com
… effectiveness of antibodies induced by infection with earlier SARS-CoV-2 variants to …
Antibody isotype diversity against SARS-CoV-2 is associated with differential serum neutralization

Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern

H Cho, KK Gonzales-Wartz, D Huang, M Yuan… - Science translational …, 2021 - science.org
antibodies in three different neutralization assays. Authentic … For antibodies that were
originally of the IgA isotype, we … antibodies that target diverse regions of the SARS-CoV-2 spike …