[HTML][HTML] Anticancer platelet-mimicking nanovehicles

Q Hu, W Sun, C Qian, C Wang… - … (Deerfield Beach, Fla.), 2015 - ncbi.nlm.nih.gov
… (PM)-coated core-shell nanovehicle (designated PM-NV) for … deliver anticancer therapeutics
to their most active destinations. To demonstrate our hypothesis, we loaded two anticancer

Cancer‐associated‐platelet‐inspired nanomedicines for cancer therapy

M Geranpayehvaghei, B Dabirmanesh… - Wiley …, 2021 - Wiley Online Library
… can be used for targeted anticancer drug delivery, due to their … be utilized to deliver anticancer
drugs or platelets inhibitors … ) (PLGA)-based platelet-mimicking nanoparticle to deliver the …

Bioinspired platelet-like nanovector for enhancing cancer therapy via p-selectin targeting

S Wan, Y Wu, Q Fan, G Yang, H Hu, S Tima… - Pharmaceutics, 2022 - mdpi.com
… Future studies are planned to confirm the in vivo targeting capacity of CCM@PL as well
as in vivo anticancer effect. Thus far, the anticancer effect of the emerging biomimetic …

Platelet-mimicking biotaxis targeting vasculature-disrupted tumors for cascade amplification of hypoxia-sensitive therapy

M Zhang, JJ Ye, Y Xia, ZY Wang, CX Li, XS Wang… - ACS …, 2019 - ACS Publications
… between vascular disruption and platelet-mimicking biotaxis for the … antitumor potency
via the biologically driven cooperation among intratumoral vascular disruption, platelet-mimicking

Human Nanoplatelets as Living Vehicles for Tumor-Targeted Endocytosis In Vitro and Imaging In Vivo

L Dai, Y Liu, S Ding, X Wei, B Chen - Journal of Clinical Medicine, 2023 - mdpi.com
… Nanoplatelets represent a new class of living nano-vehicles that may efficiently target
and deliver therapeutic agents and imaging probes to diseased tissues including tumors. …

Biomimetic “nanoplatelets” as a targeted drug delivery platform for breast cancer theranostics

L Li, J Fu, X Wang, Q Chen, W Zhang… - ACS Applied Materials …, 2021 - ACS Publications
Breast cancer is a major threat to health and lives of females. Biomimetic nanotechnology
brought brighter hope for early diagnosis and treatment of breast cancer. Here, we proposed a …

Platelets and their biomimetics for regenerative medicine and cancer therapies

Z Li, S Hu, K Cheng - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
… Her research focuses on the development of anticancer drug … Hu et al. exploited a
platelet-mimicking nanovehicle (PM-NV) … of platelet and platelet-mimicking nanomaterial-based …

Inhibition of growth of hepatocellular carcinoma by co-delivery of anti-PD-1 antibody and sorafenib using biomimetic nano-platelets

X Da, B Cao, J Mo, Y Xiang, H Hu, C Qiu, C Zhang… - BMC cancer, 2024 - Springer
… In conclusion, we hypothesize that nanovehicles (PLTM-HMSNs) coated by platelet … anticancer
drugs to the most active areas. To prove our hypothesis, we loaded two anticancer drugs, …

T cell-mimicking platelet-drug conjugates

Y Yang, Y Wang, Y Yao, S Wang, Y Zhang, G Dotti… - Matter, 2023 - cell.com
Cancer metastasis is the leading cause of cancer-related deaths. The indispensable role of
platelets in tumor metastasis inspires the targeted delivery strategy by using platelet-drug …

A Platelet-Powered Drug Delivery System for Enhancing Chemotherapy Efficacy for Liver Cancer Using the Trojan Horse Strategy

H Huang, X Wang, Z Gao, H Bao, X Yuan… - …, 2024 - pmc.ncbi.nlm.nih.gov
… Focusing on restructuring the tumor microenvironment to enhance the efficacy of
chemotherapy, our findings represent a novel method for augmenting the antitumor effect of …