[PDF][PDF] Antifungal activity of peruvian banana peel (Musa paradisiaca L.) on candida albicans: An in vitro study
M Loyaga-Castillo, RD Calla-Poma… - Journal of …, 2020 - researchgate.net
M Loyaga-Castillo, RD Calla-Poma, R Calla-Poma, MF Requena-Mendizabal…
Journal of Contemporary Dental Practice, 2020•researchgate.netAim: The purpose of this study was to compare the antifungal activity of three concentrations
of a hydroethanolic extract of the Musa× paradisiaca peel against Candida albicans strain
ATCC 10231. Materials and methods: The agar diffusion method was used, and the culture
medium used was Sabouraud agar. Petri dishes were prepared with concentrations of 10,
30, and 50% of hydroethanolic extract of the M.× paradisiaca peel; nystatin was used as a
positive control, and 96% ethanol was used as a negative control. After 24 hours of …
of a hydroethanolic extract of the Musa× paradisiaca peel against Candida albicans strain
ATCC 10231. Materials and methods: The agar diffusion method was used, and the culture
medium used was Sabouraud agar. Petri dishes were prepared with concentrations of 10,
30, and 50% of hydroethanolic extract of the M.× paradisiaca peel; nystatin was used as a
positive control, and 96% ethanol was used as a negative control. After 24 hours of …
Abstract
Aim: The purpose of this study was to compare the antifungal activity of three concentrations of a hydroethanolic extract of the Musa× paradisiaca peel against Candida albicans strain ATCC 10231.
Materials and methods: The agar diffusion method was used, and the culture medium used was Sabouraud agar. Petri dishes were prepared with concentrations of 10, 30, and 50% of hydroethanolic extract of the M.× paradisiaca peel; nystatin was used as a positive control, and 96% ethanol was used as a negative control. After 24 hours of incubation, each plate was examined, and the diameters (mm) of the growth inhibition halos were measured around each well using a digital vernier caliper.
Results: The results showed that the antifungal activity of the extract varied, depending on the concentration, as shown using analysis of variance (ANOVA; p< 0.05). When comparing the different concentrations, it was found by Duncan test that the greatest activity was obtained at 50%. Conclusion: It was concluded that the hydroethanolic extract of M.× paradisiaca at 50% exerted a greater antifungal effect on the strain of C. albicans than did the extract at lower concentrations.
Clinical significance: By knowing the antimicrobial effect of M.× paradisiaca, this substance can be effectively used in products aimed to cure candidiasis infection.
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