… activity of type II and III adenosines. In general, the antimalarial activity of disubstituted
adenosine derivatives of … to 26 μM) to the observed antimalarial effect along N 6 -monosubstituted …

… We have investigated the in vitro antimalarial activity of a new series of adenosine derivatives.
The results show that N 6 -(1-naphthylmethyl)-5‘-deoxy-5‘-(amido)adenosines as well as …

… falciparum erythrocytic stages of chloroquine resistant K1 strain. IC50 for standard drug …
To a solution of N6-substituted adenosine 5, 6 or 7 in 17.8 mL of freshly dried THF (sodium/…

… There are a number of nucleoside based A1 AR agonists with anticonvulsant activity that
have been developed over the years. Some of N6-substituted adenosine derivatives include N6…

… 1-N-Alkylation of adenosine followed by the Dimroth re… for the preparation of N6-substituted
adenosine derivatives [93]. It … Antimalarial activity of N6-substituted adenosine derivatives (…

… This paperdescribes the reactions of adenine, A^-methyladenine, and adenosine with different
… isocyanates gave the N6-substituted compound III as the major product along with some …

… Instead for the fluorescent probe only the first synthesised derivative (compound 3) was …
part of this work. We developed a series of derivatives related to the 1,2,4-triazolo[1,5-a]-1,3,5-…

… Substituted adenosine analogues … antimalarial chemotherapy.[1] Continuing these efforts,
we have investigated the in vitro antimalarial activity of a new series of adenosine derivatives 5 …

… It has been shown that the direct alkylation of adenosine with … [ Citation 21 ] 1-N-alkylation
of adenosine in DMF at rt by … work, we reinvestigated direct alkylation of adenosine and 2′-…

… From among a series of N6-substituted adenosine derivatives, compound 71 showed
potent antimalarial activity in vitro (IC50 = 8 µM) (55). In a serendipitous result, from …