Antioxidant diterpenoids from the roots of Salvia barrelieri

U Kolak, A Kabouche, M Öztürk… - Phytochemical …, 2009 - Wiley Online Library
Phytochemical analysis, 2009Wiley Online Library
Introduction The phytochemical and biological studies carried out on Salvia species showed
that their extracts and constituents have various biological activities. Objective The aim of
this study was the isolation of diterpenoids from the roots of Salvia barrelieri Ettling and the
determination of the antioxidant activity. Methodology Chromatographic methods were used
for fractionation and isolation, respectively. Structure elucidation was established by
spectroscopic methods. Five antioxidant assays were performed. Results Three new …
Introduction
The phytochemical and biological studies carried out on Salvia species showed that their extracts and constituents have various biological activities.
Objective
The aim of this study was the isolation of diterpenoids from the roots of Salvia barrelieri Ettling and the determination of the antioxidant activity.
Methodology
Chromatographic methods were used for fractionation and isolation, respectively. Structure elucidation was established by spectroscopic methods. Five antioxidant assays were performed.
Results
Three new abietane diterpenoids barreliol, royleanone 12‐methyl ether and 7‐epi‐salviviridinol, and six known diterpenoids, with a known dammarane triterpenoid, pyxinol were isolated. The absolute stereochemistry of pyxinol was confirmed by X‐ray analysis.
Conclusion
Taxodione exhibited the highest antioxidant activity among the tested compounds. Copyright © 2009 John Wiley & Sons, Ltd.
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