Apigenin ameliorates HFD-induced NAFLD through regulation of the XO/NLRP3 pathways
Y Lv, X Gao, Y Luo, W Fan, T Shen, C Ding… - The Journal of nutritional …, 2019 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver-related
morbidity and mortality disease in the world. However, no effective pharmacological
treatment for NAFLD has been found. In this study, we used a high fat diet (HFD)-induced
NAFLD model to investigate hepatoprotective effect of apigenin (API) against NAFLD and
further explored its potential mechanism. Our results demonstrated that gavage
administration of API could mitigate HFD-induced liver injury, enhance insulin sensitivity and …
morbidity and mortality disease in the world. However, no effective pharmacological
treatment for NAFLD has been found. In this study, we used a high fat diet (HFD)-induced
NAFLD model to investigate hepatoprotective effect of apigenin (API) against NAFLD and
further explored its potential mechanism. Our results demonstrated that gavage
administration of API could mitigate HFD-induced liver injury, enhance insulin sensitivity and …
Apigenin ameliorates HFD-induced NAFLD through regulation of the XO/NLRP3 pathways.
LYN Lv YaNan, GXN Gao XiaoNa, LY Luo Yan… - 2019 - cabidigitallibrary.org
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver-related
morbidity and mortality disease in the world. However, no effective pharmacological
treatment for NAFLD has been found. In this study, we used a high fat diet (HFD)-induced
NAFLD model to investigate hepatoprotective effect of apigenin (API) against NAFLD and
further explored its potential mechanism. Our results demonstrated that gavage
administration of API could mitigate HFD-induced liver injury, enhance insulin sensitivity and …
morbidity and mortality disease in the world. However, no effective pharmacological
treatment for NAFLD has been found. In this study, we used a high fat diet (HFD)-induced
NAFLD model to investigate hepatoprotective effect of apigenin (API) against NAFLD and
further explored its potential mechanism. Our results demonstrated that gavage
administration of API could mitigate HFD-induced liver injury, enhance insulin sensitivity and …
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