Application of computational fluid dynamics in tissue engineering

AR Patrachari, JT Podichetty, SV Madihally - Journal of bioscience and …, 2012 - Elsevier
The process of tissue regeneration consists of a set of complex phenomena such as
hydrodynamics, nutrient transfer, cell growth, and matrix deposition. Traditional cell culture
and bioreactor design procedure follow trial-and-error analyses to understand the effects of
varying physical, chemical, and mechanical parameters that govern the process of tissue
regeneration. This trend has been changing as computational fluid dynamics (CFD) analysis
can now be used to understand the effects of flow, cell proliferation, and consumption …
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