Aptamer biosensor design for the detection of endocrine-disrupting chemicals small organic molecules using novel bioinformatics methods

I Bayıl, MS Hossain, S Tamanna, MJ Uddin… - Journal of Molecular …, 2024 - Elsevier
Endocrine-disrupting chemicals (EDCs) are substances that can disrupt the normal
functioning of hormones. Using aptamers, which are biological recognition elements,
biosensors can quickly and accurately detect EDCs in environmental samples. However, the
elucidation of aptamer structures by conventional methods is highly challenging due to their
complexity. This has led to the development of three-dimensional aptamer structures based
on different models and techniques. To do this, we developed a way to predict the 3D …
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