One of the strategies for sustainable development is to promote a quality health care system, available to all without discrimination, and improving protection against health threats. In this context, arsenic removal from groundwater for drinking purposes presents challenges at national and global levels. Thus, the present article focuses on removing arsenic from groundwaters by using a new class of materials based on cellulose modified with crown ether (dibenzo-18-crown-6) doped with iron ions. Using such extractants involves only a small amount of crown ether, indicating higher efficiency of produced material, and in order to improve the adsorbent properties and selectivity for arsenic removal, the modified cellulose was functionalized with iron ions.