Aspirin dose and prevention of coronary abnormalities in Kawasaki disease

F Dallaire, Z Fortier-Morissette, S Blais… - …, 2017 - publications.aap.org
BACKGROUND: Acetylsalicylic acid (ASA) is part of the recommended treatment of
Kawasaki disease (KD). Controversies remain regarding the optimal dose of ASA to be
used. We aimed to evaluate the noninferiority of ASA at an antiplatelet dose in acute KD in
preventing coronary artery (CA) abnormalities. METHODS: This is a multicenter,
retrospective, nonrandomized cohort study including children 0 to 10 years of age with acute
KD between 2004 and 2015 from 5 institutions, of which 2 routinely use low-dose ASA (3–5 …
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