The study was undertaken in and around the industrial establishments located in Ankleshwar region of Gujarat, India for understanding the variation in Cd, Cr, Cu, Mn and Ni level of groundwater in pre-and post-monsoon periods. The concentration of Cd exceeded the acceptable limits of BIS 2012 for drinking water in both the seasons whereas Cr, Cu, Mn and Ni had concentration levels above acceptable limits in the pre-monsoon season and below acceptable limits in the post-monsoon season. The average HPI value in the pre-monsoon season was 537.2 and it came down to 359.5 in the post-monsoon season, but these values exceeded the critical value of 100 in both the seasons and they were attributable to the discharge of effluents from the industries. Spatial distribution map was prepared using GIS for a better understanding of the levels of heavy metals contamination in the sampling sites.