Association between ambient air pollution and amyloid positron emission tomography positivity in older adults with cognitive impairment

L Iaccarino, R La Joie, OH Lesman-Segev… - JAMA …, 2021 - jamanetwork.com
Importance Amyloid-β (Aβ) deposition is a feature of Alzheimer disease (AD) and may be
promoted by exogenous factors, such as ambient air quality. Objective To examine the
association between the likelihood of amyloid positron emission tomography (PET) scan
positivity and ambient air quality in individuals with cognitive impairment. Design, Setting,
and Participants This cross-sectional study used data from the Imaging Dementia—
Evidence for Amyloid Scanning Study, which included more than 18 000 US participants …
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