Association between genetic traits for immune-mediated diseases and Alzheimer disease

JS Yokoyama, Y Wang, AJ Schork… - JAMA …, 2016 - jamanetwork.com
Importance Late-onset Alzheimer disease (AD), the most common form of dementia, places
a large burden on families and society. Although epidemiological and clinical evidence
suggests a relationship between inflammation and AD, their relationship is not well
understood and could have implications for treatment and prevention strategies. Objective
To determine whether a subset of genes involved with increased risk of inflammation are
also associated with increased risk for AD. Design, Setting, and Participants In a genetic …
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