[PDF][PDF] Association between polymorphisms in the thymidylate synthase gene and risk of breast cancer in a Mexican population
A Quintero-Ramos, SA Gutiérrez-Rubio… - Genet Mol …, 2014 - researchgate.net
A Quintero-Ramos, SA Gutiérrez-Rubio, A Del Toro-Arreola, RA Franco-Topete…
Genet Mol Res, 2014•researchgate.net… We examined the association between these polymorphisms and BC risk in Mexican
women according to menopause status. Mexican patients with initial BC diagnosis (N = 230)
and 145 individuals from a reference general population group (RGP) were included. For
statistical analysis, the BC group was divided into pre- and post-menopause groups (PRE
and POST groups, respectively). … Polymorphic tandem repeats in the thymidylate
synthase gene is associated with its protein expression in human gastrointestinal cancers …
women according to menopause status. Mexican patients with initial BC diagnosis (N = 230)
and 145 individuals from a reference general population group (RGP) were included. For
statistical analysis, the BC group was divided into pre- and post-menopause groups (PRE
and POST groups, respectively). … Polymorphic tandem repeats in the thymidylate
synthase gene is associated with its protein expression in human gastrointestinal cancers …
Abstract
Breast cancer (BC) is the leading cause of cancer-related deaths among women in Mexico. Two single-nucleotide polymorphisms (SNPs) in the thymidylate synthase (TS) gene, the 28-base pair (bp)
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