Association of glyburide and subcutaneous insulin with perinatal complications among women with gestational diabetes
Importance Nearly 30% of individuals with gestational diabetes (GDM) do not achieve
glycemic control with lifestyle modification alone and require medication treatment. Oral
agents, such as glyburide, have several advantages over insulin for the treatment of GDM,
including greater patient acceptance; however, the effectiveness of glyburide for the
treatment of GDM remains controversial. Objective To compare the perinatal and neonatal
outcomes associated with glyburide vs insulin using causal inference methods in a clinical …
glycemic control with lifestyle modification alone and require medication treatment. Oral
agents, such as glyburide, have several advantages over insulin for the treatment of GDM,
including greater patient acceptance; however, the effectiveness of glyburide for the
treatment of GDM remains controversial. Objective To compare the perinatal and neonatal
outcomes associated with glyburide vs insulin using causal inference methods in a clinical …
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