Importance Although previous studies have evaluated the association between anti–
vascular endothelial growth factor therapy and macular vessel density, they were
confounded by the presence of macular edema, which may be associated with artifacts and
segmentation errors in optical coherence tomography angiography (OCTA). Objective To
evaluate the association of intravitreal aflibercept with changes in macular vascular density
using OCTA in patients with proliferative diabetic retinopathy without diabetic macular …