Aquaculture is a growing industry, increasing the need for understanding host–pathogen
interactions in fish. The skin and mucosal surfaces, covered by a mucus layer composed of
mucins, is the first point of contact between fish and pathogens. Highly O-glycosylated
mucins have been shown to be an important part of the defense against pathogens, and
pathogens bind to host surfaces using lectin-like adhesins. However, knowledge of piscine
O-glycosylation is very limited. We characterized mucin O-glycosylation of five freshwater …