Attenuation of quorum sensing regulated virulence and biofilm development in Pseudomonas aeruginosa PAO1 by Diaporthe phaseolorum SSP12

SS Pattnaik, SK Ranganathan, DR Ampasala… - Microbial …, 2018 - Elsevier
In recent years, Pseudomonas aeruginosa PAO1 emerged as the significant pathogenic
microorganism in majority of the hospital-acquired infections due to its resistance to the
conventional antibiotics by virtue of its highly organized quorum sensing and associated
biofilm formation. In the present study, quorum sensing attenuation potential of Diaporthe
phaseolorum SSP12 extract was investigated against P. aeruginosa PAO1 amply supported
by molecular docking studies. D. phaseolorum SSP12 extract significantly inhibited the …
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